A trip induced by psilocybin chocolate bars has been described by many research participants as one of the most profound experiences in their life. From the perspective of a person with major depression looking to find relief from their debilitating illness, the trip is a side effect! What we seek is the effect on the brain which so magically relieves depression. Nevertheless the experience of a trip has invariably been described as a deeply profound and spiritual experience which has offered new insights into the human condition, so that “side effect” can be enormously beneficial.